Consider the following statistics: 

• 74% of Americans are either overweight (32%) or obese (42%) according to CDC, NHANES 2021. 

• Over 50% of the kids in the US are overweight or obese. 

• Up to 80 million US adults do not get enough sleep. Average sleep duration has declined 1.5 to 2 hours/night over the past 50 years. 

• 82% of cardiovascular events would be prevented if all women followed lifestyle management strategies; only 3% actually did. 

• Similarly, for men, 62% of cardiovascular events would be prevented if all men followed lifestyle management strategies; only 4% actually did. 

Clinical Evidence for Effectiveness of Lifestyle Intervention for Chronic Illnesses

There are many research studies that have shown the benefits of lifestyle interventions, such as diet and exercise, for various health conditions. Here are a few examples:

• The Diabetes Prevention Program, a large randomized clinical trial, found that lifestyle intervention including diet and physical activity changes reduced the development of type 2 diabetes by 58% in individuals at high risk for the disease.

• The Look AHEAD (Action for Health in Diabetes) study, a large randomized clinical trial, found that a lifestyle intervention including diet and physical activity changes resulted in weight loss and improvement in cardiovascular risk factors in individuals with type 2 diabetes.

• The Lifestyle Heart Trial, a randomized clinical trial, found that a lifestyle intervention including a low-fat, plant-based diet and regular physical activity resulted in a reversal of coronary artery disease in some individuals.

• The PREMIER trial, a randomized clinical trial, found that a lifestyle intervention including diet and physical activity changes resulted in significant improvements in blood pressure and cholesterol levels in individuals at risk for cardiovascular disease.

• The Women's Health Initiative Dietary Modification Trial, a randomized clinical trial, found that a lifestyle intervention including a low-fat diet resulted in a small but statistically significant reduction in breast cancer risk in postmenopausal women. 

Clinical Evidence for Effectiveness of Lifestyle Intervention for Weight Loss

There are many studies that have examined the effectiveness of lifestyle interventions for weight loss. Here are a few examples:

• A study published in 2021 found that a lifestyle intervention that included a low-calorie diet, increased physical activity, and behavior therapy was effective at achieving weight loss and improving cardiovascular risk factors in overweight and obese adults.

• A study published in 2016 found that a lifestyle intervention that included a low-calorie diet, increased physical activity, and behavior therapy was effective at achieving weight loss and improving cardiovascular risk factors in overweight and obese adults.

• A study published in "The Lancet Diabetes & Endocrinology" in 2018 found that a lifestyle intervention that included a low-carbohydrate diet, increased physical activity, and behavior therapy was effective at achieving weight loss and improving cardiovascular risk factors in overweight and obese adults.

• A study published in "The American Journal of Clinical Nutrition" in 2013 found that a lifestyle intervention that included a Mediterranean-style diet, increased physical activity, and behavior therapy was effective at achieving weight loss and improving cardiovascular risk factors in overweight and obese adults.

• A study published in "Obesity Reviews" in 2020 found that a lifestyle intervention that included a low-fat diet, increased physical activity, and behavior therapy was effective at achieving weight loss and improving cardiovascular risk factors in overweight and obese adults.